Publications

easyXpress, An R package to analyze and visualize high-throughput C. elegans microscopy data generated using CellProfiler
Nyaanga J Crombie TA Widmayer SJ Andersen EC
(2021 May 11) bioRxiv [ DOI ]

Physical constraints on growth dynamics guide C. elegans developmental trajectories and animal shape
Nyaanga J Goss C Zhang G Ahmed HN Andersen EJ Miller IR Rozenich JK Swarthout IL Vaughn JA Andersen EC Mangan NM Shirman S
(2021 April 3) bioRxiv [ DOI ]

Mutability of mononucleotide repeats, not oxidative stress, explains the discrepancy between laboratory-accumulated mutations and the natural allele-frequency spectrum in C. elegans
Rajaei M Saxena AS Johnson LM Snyder MC Crombie TA Tanny RE Andersen EC Joyner-Matos J Baer CF
(2021 February 10) bioRxiv [ DOI ]

Two novel loci underlie differences in Caenorhabditis elegans macrocyclic lactone responses
Evans KS Wit J Stevens L Hahnel SR Rodriguez B Park G Zamanian M Brady SC Chao E Introcaso K Tanny RE Andersen EC
(2021 March 2) PLoS Pathogens [ DOI ]

Long-term metabolomics reference material
Gouveia GJ Shaver AO Garcia BM Morse AM Rodriguez B Park G Andersen EC Edison AS McIntyre LM
(2021 March 24) bioRxiv [ DOI ]

Balancing selection maintains ancient genetic diversity in C. elegans
Lee D Zdraljevic S Stevens L Wang Y Tanny RE Crombie TA Cook DE Webster AK Chirakar R Baugh LR Sterken MG Braendle C Felix MA Rockman MV Andersen EC
(2021 February 23) Nature Ecology and Evolution [ DOI ]

Natural variation in fertility is correlated with species-wide levels of divergence in Caenorhabditis elegans
Zhang G Mostad JD Andersen EC
(2021 May 1) G3 [ DOI ]

Xenobiotic metabolism and transport in Caenorhabditis elegans
Hartman JH Widmayer SJ Bergemann CM King DE Morton KS Romersi RS Jameson LE Leung MCK Andersen EC Taubert S Meyer JN
(2021 February 22) Journal of Toxicology and Environmental Health, Part B [ DOI ]

Natural variation in Caenorhabditis elegans responses to the anthelmintic emodepside
Wit J Andersen EC
(2021 April 6) International Journal for Parasitology Drugs and Drug Resistance [ DOI ]

Selfing is the safest sex for Caenorhabditis tropicalis
Noble LM Yuen J Stevens L Moya N Persaud R Moscatelli M Jackson J Zhang G Chitrakar R Baugh LR Braendle C Andersen EC Seidel HS Rockman MV
(2021 January 11) eLife [ DOI ]

The distribution of mutational effects on fitness in Caenorhabditis elegans inferred from standing genetic variation
Gilbert KJ Zdraljevic S Cook DE Cutter AD Andersen EC Baer CF
(2020 October 26) bioRxiv [ DOI ]

Complementary Approaches to Understand Anthelmintic Resistance Using Free-Living and Parasitic Nematodes
Wit J Dilks C Andersen EC
(2020 December 13) Trends in Parasitology [ DOI ]

Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans
Evans KS Zdraljevic S Stevens L Collins K Tanny RE Andersen EC
(2020 November 11) PLoS Genetics [ DOI ]

Caenorhabditis elegans in anthelmintic research - Old model, new perspectives
Hahnel SR Dilks CM Heisler I Andersen EC Kulke D
(2020 September 26) International Journal for Parasitology Drugs and Drug Resistance [ DOI ]

The cadmium-responsive gene, cdr-6, does not influence Caenorhabditis elegans responses to exogenous zinc
Evans KS Andersen EC
(2020 September 5) microPublication [ DOI ]

Culture and assay of large-scale mixed-stage Caenorhabditis elegans populations
Shaver AO Gouveia GJ Kirby PS Andersen EC Edison AS
(2020 August 26) Journal of Visualized Experiments [ DOI ]

Quantitative benzimidazole resistance and fitness effects of parasitic nematode beta-tubulin alleles
Dilks CM Hahnel SR Sheng Q Long L McGrath PT Andersen EC
(2020 August 5) International Journal for Parasitology Drugs and Drug Resistance [ DOI ]

Natural variation in a glucuronosyltransferase modulates propionate sensitivity in a C. elegans propionic acidemia model
Na H Zdraljevic S Tanny RE Walhout AJM Andersen EC
(2020 July 3) PLoS Genetics [ DOI ]

The gene scb-1 underlies variation Caenorhabditis elegans chemotherapeutic responses
Evans KS Andersen EC
(2020 May 8) G3 [ DOI | Pubmed ]

The nematode Caenorhabditis elegans nematodes and the terrestrial isopod Porcellio scaber likely interact opportunistically
Archer H Deiparine S Andersen EC
(2020 June 26) PLoS ONE [ DOI | Pubmed ]

A spontaneous complex structural variant in rcan-1 increases exploratory behavior and laboratory fitness of Caenorhabditis elegans
Zhao Y Long L Wan J Biliya S Brady SC Lee D Ojemakinde A Andersen EC Vannberg FO Lu H McGrath PT
(2020 February 24) PLoS Genetics [ DOI | Pubmed ]

Effects of telomerase overexpression in the model organism Caenorhabditis elegans
Bayat M Tanny RE Wang Y Herden C Daniel J Andersen EC Liebau E Waschk DEJ
(2020 January 16) Gene [ DOI | Pubmed ]

Selection and gene flow shape niche-associated variation of pheromone response
Lee D Zdraljevic S Frezal L Hsu J Sterken MG Riksen JAG Wang J Kammenga JE Braendle C Felix A Schroeder FC Andersen EC
(2019 March 26) Nature Ecology and Evolution [ DOI | Pubmed | PMC ]

An escape-room inspired game for genetics review
Brady SC Andersen EC
(2019 December 6) Journal of Biological Education [ ]

Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations
Crombie TA Zdraljevic S Cook DE Tanny RE Brady SC Wang Y Evans KS Hahnel S Lee D Rodriguez BC Zhang G van der Zwaag J Kiontke KC Andersen EC
(2019 November 6) eLife [ DOI | Pubmed | PMC ]

Population selection and sequencing of Caenorhabditis elegans wild isolates identifies a region on chromosome III affecting starvation resistance
Webster AK Hung A Moore BT Guzman R Jordan JM Kaplan REW Hibshman JD Tanny RE Cook DE Andersen EC Baugh LR
(2019 September 6) G3 [ DOI | Pubmed | PMC ]

Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans
Kim C Kim J Kim S Cook DE Evans KS Andersen EC Lee J
(2019 May 23) Genome Research [ DOI | Pubmed ]

Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism
Zdraljevic S Fox BW Strand C Panda O Tenjo FJ Brady SC Crombie TA Doench JG Schroeder FC Andersen EC
(2019 Apr 08) eLife [ DOI | Pubmed | PMC ]

A novel gene underlies bleomycin-response variation in Caenorhabditis elegans
Brady SC Zdraljevic S Bisaga KW Tanny RE Cook DE Lee D Wang Y Andersen EC
(2019 May 30) Genetics [ DOI | Pubmed ]

Evolution of sperm competition - Natural variation and genetic determinants of Caenorhabditis elegans sperm size
Gimond C Vielle A Soares NS Zdraljevic S McGrath P Andersen EC Braendle C
(2018 Dec 19) Genetics [ DOI | Pubmed | PMC ]

Tightly linked antagonistic-effect loci underlie polygenic demographic variation in C. elegans
Bernstein MR Zdraljevic S Andersen EC Rockman MV
(2018 Sep 27) Evolution Letters [ DOI | Pubmed | PMC ]

Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles
Hahnel SR Zdraljevic S Rodriguez BC Zhao Y McGrath PT Andersen EC
(2018 Oct 29) PLOS Pathogens [ DOI | Pubmed | PMC ]

Shared Genomic Regions Underlie Natural Variation in Diverse Toxin Responses
Evans KS Brady SC Bloom JS Tanny RE Cook DE Giuliani SE Hippleheuser SW Zamanian M Andersen EC
(2018 Oct 19) Genetics [ DOI | Pubmed | PMC ]

Discovery of genomic intervals that underlie nematode responses to benzimidazoles
Zamanian M Cook DE Zdraljevic S Brady SC Lee D Lee J Andersen EC
(2018 Mar 5) PLoS Negl Trop Dis [ DOI | Pubmed ]

Natural diversity facilitates the discovery of conserved chemotherapeutic response mechanisms
Zdraljevic S Andersen EC
(2017 Sept 09) Curr. Opin. Genet. Dev. [ DOI | Pubmed ]

The genetic basis of natural variation in a phoretic behavior
Lee D Yang H Kim J Brady S Zdraljevic S Zamanian M Kim H Paik YK Kruglyak L Andersen EC Lee J
(2017 Aug 17) Nat Commun [ DOI | Pubmed | PMC ]

Natural variation in a single amino acid underlies cellular responses to topoisomerase II poisons
Zdraljevic S Strand C Seidel HS Cook DE Doench JG Andersen EC
(2017 Apr 07) PLOS Genetics [ DOI | Pubmed | Data ]

VCF-kit - Assorted utilities for the variant call format
Cook DE Andersen EC
(2017 Jan 16) Bioinformatics [ DOI | Pubmed ]

Natural variation in the distribution and abundance of transposable elements across the Caenorhabditis elegans species
Laricchia KM Zdraljevic S Cook DE Andersen EC
(2017 May 09) Molecular Biology and Evolution [ DOI | Pubmed | Data ]

Copper Oxide Nanoparticles Impact Several Toxicological Endpoints and Cause Neurodegeneration in Caenorhabditis elegans
Mashock MJ Zanon T Kappell AD Petrella LN Andersen EC Hristova KR
(2016 Dec 2) PLoS ONE [ DOI | Pubmed ]

Correlations of geneotype with climate parameters suggest Caenorhabditis elegans niche adaptations
Evans KS Zhao Y Brady SC Long L McGrath PT Andersen EC
(2016 Nov 18) G3 [ DOI | Pubmed | Data ]

CeNDR, the Caenorhabditis elegans natural diversity resource
Cook DE Zdraljevic S Roberts JP Andersen EC
(2016 Oct 3) Nucleic Acids Research [ DOI | Pubmed ]

The genetic basis of natural variation in C. elegans telomere length
Cook DE Zdraljevic S Tanny RE Seo B Riccardi DD Noble LM Rockman MV Alkema MJ Braendle C Kammenga JE Wang J Kruglyak L Félix MA Lee J Andersen EC
(2016 Sep 1) Genetics [ DOI | Pubmed | Data ]

Mutation Is a Sufficient and Robust Predictor of Genetic Variation for Mitotic Spindle Traits in Caenorhabditis elegans
Farhadifar R Ponciano JM Andersen EC Needleman DJ Baer CF
(2016 Aug 1) Genetics [ DOI | Pubmed | PMC ]

Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans
Large EE Xu W Zhao Y Brady SC Long L Butcher RA Andersen EC McGrath PT
(2016 July 28) PLoS Genet. [ DOI | Pubmed ]

Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases
Zamanian M Andersen EC
(2016 July 11) FEBS Journal [ DOI | Pubmed ]

Remarkably Divergent Regions Punctuate the Genome Assembly of the Caenorhabditis elegans Hawaiian Strain CB4856
Thompson OA Snoek LB Nijveen H Sterken MG Volkers RJM Brenchley R van 't Hof A Bevers RPJ Cossins AR Yanai I Hajnal A Schmid T Perkins JD Spencer D Kruglyak L Andersen EC Moerman DG Hillier LW Kammenga JE Waterston RH
(2015 May 19) Genetics [ DOI | Pubmed ]

The laboratory domestication of Caenorhabditis elegans
Sterken MG Snoek LB Kammenga JE Andersen EC
(2015 Mar 21) Trends in Genetics [ DOI | Pubmed ]

A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains
Andersen EC Shimko TC Crissman JR Ghosh R Bloom JS Seidel HS Gerke JP Kruglyak L
(2015 Mar 13) G3 (Bethesda) [ DOI | Pubmed | Data ]

Scaling, Selection, and Evolutionary Dynamics of the Mitotic Spindle
Farhadifar R Baer CF Valfort AC Andersen EC Muller-Reichert T Delattre M Needleman DJ
(2015 Feb 11) Current Biology [ DOI | Pubmed ]

The red death meets the abdominal bristle - Polygenic mutation for susceptibility to a bacterial pathogen in Caenorhabditis elegans.'
Etienne V Andersen EC Ponciano JM Blanton D Cadavid A Joyner-Matos J Matsuba C Tabman B Baer CF
(2015 Feb) Evolution [ DOI | Pubmed | PMC ]

A wild C. elegans strain has enhanced epithelial immunity to a natural microsporidian parasite.
Balla KM Andersen EC Kruglyak L Troemel ER
(2015 Feb) PLoS Pathogens [ DOI | Pubmed | PMC ]

COPASutils - An R Package for Reading, Processing, and Visualizing Data from COPAS Large-Particle Flow Cytometers
Shimko TC Andersen EC
(2014 Oct 20) PLoS One [ DOI | Pubmed | PMC ]

A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology
Andersen EC Bloom JS Gerke JP Kruglyak L
(2014 Feb) PLoS Genetics [ DOI | Pubmed | PMC ]

Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest
Felix MA Jovelin R Ferrari C Han S Cho YR Andersen EC Cutter AD Braendle C
(2013 Jan 12) BMC Evolutionary Biology [ DOI | Pubmed | PMC ]

Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans
Ghosh R Andersen EC Shapiro JA Gerke JP Kruglyak L
(2012 Feb 3) Science [ DOI | Pubmed | PMC ]

Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity
Andersen EC Gerke JP Shapiro JA Crissman JR Ghosh R Bloom JS Felix MA Kruglyak L
(2012 Mar) Nature Genetics [ DOI | Pubmed | PMC | Data ]

PCR-directed in vivo plasmid construction using homologous recombination in bakers yeast
Andersen EC
(2011 Jul 08) Methods in Molecular Biology [ DOI | Pubmed ]

Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line.
Bessler JB Andersen EC Villeneuve AM
(2010 Jan) PLoS Genetics [ DOI | Pubmed | PMC ]

Variability in gene expression underlies incomplete penetrance
Raj A Rifkin SA Andersen EC van Oudenaarden A
(2010 Feb 18) Nature [ DOI | Pubmed | PMC ]

A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans
Reddy KC Andersen EC Kruglyak L Kim DH
(2009 Jan 16) Science [ DOI | Pubmed | PMC ]

Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates
Andersen EC Saffer AM Horvitz HR
(2008 Aug) Genetics [ DOI | Pubmed | PMC ]

Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development
Andersen EC Horvitz HR
(2007 Aug) Development [ DOI | Pubmed ]

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans
Reddien PW Andersen EC Huang MC Horvitz HR
(2007 Apr) Genetics [ DOI | Pubmed | PMC ]

C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates
Andersen EC Lu X Horvitz HR
(2006 Jul) Development [ DOI | Pubmed ]

Patterns of gene expression during Drosophila mesoderm development
Furlong EE Andersen EC Null B White KP Scott MP
(2001 Aug 31) Science [ DOI | Pubmed ]